![C41H51N5O8Si Guanozino, 5′-O-[bis(4-metoxifenil)fenilmetil]-2′-O-[(1,1-dimetiletil)dimetilsilil]-N-(2-metil-1-oxopropil)- (9CI, ACI )](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![C41H51N5O8Si Guanozino, 5′-O-[bis(4-metoxifenil)fenilmetil]-2′-O-[(1,1-dimetiletil)dimetilsilil]-N-(2-metil-1-oxopropil)- (9CI, ACI ) Elstara Bildo](https://cdn.globalso.com/nvchem/C41H51N5O8Si-Guanosine.jpg)
C41H51N5O8Si Guanozino, 5′-O-[bis(4-metoxifenil)fenilmetil]-2′-O-[(1,1-dimetiletil)dimetilsilil]-N-(2-metil-1-oxopropil)- (9CI, ACI )
| Ŝlosilaj Fizikaj Propraĵoj | Valoro | Kondiĉo |
| Molekula pezo | 769,96 | - |
| Denso (Antaŭvidita) | 1,25±0,1 g/cm3 | Temp: 20 °C;Gazetaro: 760 Torr |
| pKa (Antaŭvidita) | 9,16±0,20 | Plej Acida Temp: 25 °C |
Kanonaj RIDETOJ O=C1N=C(NC(=O)C(C)C)NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6= CC=C(OC)C=C6)C(O)C3O[Si](C)(C)C(C)(C)C
Isomeraj RIDETOJ
C(OC[C@H]1O[C@H]([C@H](O[Si](C(C)(C)C)(C)C)[C@@H]1O)N2C3= C(N=C2)C(=O)N=C(NC(C(C)C)=O)N3)(C4=CC=C(OC)C=C4)(C5=CC=C(OC) C=C5)C6=CC=CC=C6
InChI
InChI=1S/C41H51N5O8Si/c1-25(2)36(48)44-39-43-35-32(37(49)45-39)42-24-46(35)38-34(54-55() 8,9)40(3,4)5)33(47)31(53-38)23-52-41(2 6-13-11-10-12-14-26,27-15-19-29 (50-6)20-16-27)28-17-21-30(51-7)22-18-28/h10-22,24-25,31,33-34,38,47H,23H2,1 -9H3,(H2,43,44,45,
48,49)/t31-,33-,34-,38-/m1/s1
InChI Ŝlosilo
JMCNKJFOIJGYRG-CJEGOSRCSA-N
1 Alia Nomo por ĉi tiu Substanco
5′-O-[Bis(4-metoxifenil)fenilmetil]-2′-O-[(1,1-dimetiletil)dimetilsilil]-N-(2-metil-1-oxopropil)guanozino (ACI)
Spektro haveblaj
1H NMR
13C NMR
Meso
| Disponeblaj posedaĵoj |
| Biologia |
| Kemiaĵo |
| Denso |
| Lipinski |
| Strukturo Rilata |
Biologia
| Proprieto | Valoro | Kondiĉo | Fonto |
| Biokoncentra Faktoro | 1,38 x 105 | pH 1;Temperaturo: 25 °C | (1) ACD |
| Biokoncentra Faktoro | 3,53 x 105 | pH 2;Temperaturo: 25 °C | (1) ACD |
| Biokoncentra Faktoro | 4,18 x 105 | pH 3;Temperaturo: 25 °C | (1) ACD |
| Biokoncentra Faktoro | 4,26 x 105 | pH 4;Temperaturo: 25 °C | (1) ACD |
| Biokoncentra Faktoro | 4,26 x 105 | pH 5;Temperaturo: 25 °C | (1) ACD |
| Biokoncentra Faktoro | 4,26 x 105 | pH 6;Temperaturo: 25 °C | (1) ACD |
| Biokoncentra Faktoro | 4,21 x 105 | pH 7;Temperaturo: 25 °C | (1) ACD |
| Biokoncentra Faktoro | 3,77 x 105 | pH 8;Temperaturo: 25 °C | (1) ACD |
| Biokoncentra Faktoro | 1,86 x 105 | pH 9;Temperaturo: 25 °C | (1) ACD |
| Biokoncentra Faktoro | 33800 | pH 10;Temperaturo: 25 °C | (1) ACD |
(1) Kalkulite uzante Advanced Chemistry Development (ACD/Labs) Programaro V11.02 (© 1994-2023 ACD/Labs)
Kemiaĵo
| Proprieto | Valoro | Kondiĉo | Fonto |
| Koc | 1,21 x 105 | pH 1;Temperaturo: 25 °C | (1) ACD |
| Koc | 3,08 x 105 | pH 2;Temperaturo: 25 °C | (1) ACD |
| Koc | 3,65 x 105 | pH 3;Temperaturo: 25 °C | (1) ACD |
| Koc | 3,72 x 105 | pH 4;Temperaturo: 25 °C | (1) ACD |
| Koc | 3,73 x 105 | pH 5;Temperaturo: 25 °C | (1) ACD |
| Koc | 3,72 x 105 | pH 6;Temperaturo: 25 °C | (1) ACD |
| Koc | 3,68 x 105 | pH 7;Temperaturo: 25 °C | (1) ACD |
| Proprieto | Valoro | Kondiĉo | Fonto |
| Koc | 3,30 x 105 | pH 8;Temperaturo: 25 °C | (1) ACD |
| Koc | 1,62 x 105 | pH 9;Temperaturo: 25 °C | (1) ACD |
| Koc | 29600 | pH 10;Temperaturo: 25 °C | (1) ACD |
| logD | 7.22 | pH 1;Temperaturo: 25 °C | (1) ACD |
| logD | 7.63 | pH 2;Temperaturo: 25 °C | (1) ACD |
| logD | 7.70 | pH 3;Temperaturo: 25 °C | (1) ACD |
| logD | 7.71 | pH 4;Temperaturo: 25 °C | (1) ACD |
| logD | 7.71 | pH 5;Temperaturo: 25 °C | (1) ACD |
| logD | 7.71 | pH 6;Temperaturo: 25 °C | (1) ACD |
| logD | 7.70 | pH 7;Temperaturo: 25 °C | (1) ACD |
| logD | 7.66 | pH 8;Temperaturo: 25 °C | (1) ACD |
| logD | 7.35 | pH 9;Temperaturo: 25 °C | (1) ACD |
| logD | 6.61 | pH 10;Temperaturo: 25 °C | (1) ACD |
| logP | 7,710±0,709 | Temperaturo: 25 °C | (1) ACD |
| Masa Intrinseka Solvebleco | 2,7 x 10-5 g/L | Temperaturo: 25 °C | (1) ACD |
| Masa Solveco | 8,5 x 10-5 g/L | pH 1;Temperaturo: 25 °C | (1) ACD |
| Masa Solveco | 3,3 x 10-5 g/L | pH 2;Temperaturo: 25 °C | (1) ACD |
| Masa Solveco | 2,8 x 10-5 g/L | pH 3;Temperaturo: 25 °C | (1) ACD |
| Masa Solveco | 2,7 x 10-5 g/L | pH 4;Temperaturo: 25 °C | (1) ACD |
| Masa Solveco | 2,7 x 10-5 g/L | pH 5;Temperaturo: 25 °C | (1) ACD |
| Masa Solveco | 2,7 x 10-5 g/L | pH 6;Temperaturo: 25 °C | (1) ACD |
| Masa Solveco | 2,8 x 10-5 g/L | pH 7;Temperaturo: 25 °C | (1) ACD |
| Masa Solveco | 3,1 x 10-5 g/L | pH 8;Temperaturo: 25 °C | (1) ACD |
| Masa Solveco | 6,2 x 10-5 g/L | pH 9;Temperaturo: 25 °C | (1) ACD |
| Masa Solveco | 3,5 x 10-4 g/L | pH 10;Temperaturo: 25 °C | (1) ACD |
| Masa Solveco | 2,8 x 10-5 g/L | Nebufrita Akvo pH 7.00;Temperaturo: 25 °C | (1) ACD |
| Molara Intrinseka Solvebleco | 3,5 x 10-8 mol/L | Temperaturo: 25 °C | (1) ACD |
| Molara Solvebleco | 1,1 x 10-7 mol/L | pH 1;Temperaturo: 25 °C | (1) ACD |
| Molara Solvebleco | 4,3 x 10-8 mol/L | pH 2;Temperaturo: 25 °C | (1) ACD |
| Molara Solvebleco | 3,6 x 10-8 mol/L | pH 3;Temperaturo: 25 °C | (1) ACD |
| Molara Solvebleco | 3,5 x 10-8 mol/L | pH 4;Temperaturo: 25 °C | (1) ACD |
| Molara Solvebleco | 3,5 x 10-8 mol/L | pH 5;Temperaturo: 25 °C | (1) ACD |
| Proprieto | Valoro | Kondiĉo | Fonto |
| Molara Solvebleco | 3,5 x 10-8 mol/L | pH 6;Temperaturo: 25 °C | (1) ACD |
| Molara Solvebleco | 3,6 x 10-8 mol/L | pH 7;Temperaturo: 25 °C | (1) ACD |
| Molara Solvebleco | 4,0 x 10-8 mol/L | pH 8;Temperaturo: 25 °C | (1) ACD |
| Molara Solvebleco | 8,1 x 10-8 mol/L | pH 9;Temperaturo: 25 °C | (1) ACD |
| Molara Solvebleco | 4,5 x 10-7 mol/L | pH 10;Temperaturo: 25 °C | (1) ACD |
| Molara Solvebleco | 3,6 x 10-8 mol/L | Nebufrita Akvo pH 7.00;Temperaturo: 25 °C | (1) ACD |
| Molekula pezo | 769,96 | ||
| pKa | 9,16±0,20 | Plej Acida Temp: 25 °C | (1) ACD |
| pKa | 1,73±0,10 | Plej Baza Temperaturo: 25 °C | (1) ACD |
(1) Kalkulite uzante Advanced Chemistry Development (ACD/Labs) Programaro V11.02 (© 1994-2023 ACD/Labs)
Denso
| Proprieto | Valoro | Kondiĉo | Fonto |
| Denso | 1,25±0,1 g/cm3 | Temp: 20 °C;Gazetaro: 760 Torr | (1) ACD |
| Molara Volumo | 615,5±7,0 cm3/mol | Temp: 20 °C;Gazetaro: 760 Torr | (1) ACD |
(1) Kalkulite uzante Advanced Chemistry Development (ACD/Labs) Programaro V11.02 (© 1994-2023 ACD/Labs)
Lipinski
| Proprieto | Valoro | Kondiĉo | Fonto |
| Libere Rotacieblaj Obligacioj | 14 | (1) ACD | |
| H Akceptantoj | 13 | (1) ACD | |
| H Donantoj | 3 | (1) ACD | |
| H Sumo de donacanto/akceptanto | 16 | (1) ACD | |
| logP | 7,710±0,709 | Temperaturo: 25 °C | (1) ACD |
| Molekula pezo | 769,96 |
(1) Kalkulite uzante Advanced Chemistry Development (ACD/Labs) Programaro V11.02 (© 1994-2023 ACD/Labs)
Strukturo Rilata
| Proprieto | Valoro | Kondiĉo | Fonto |
| Polusa Surfacareo | 155 A2 | (1) ACD | |
(1) Kalkulite uzante Advanced Chemistry Development (ACD/Labs) Programaro V11.02 (© 1994-2023 ACD/Labs)
Spektro haveblaj
1H NMR
13C NMR
![C50H60N5O10P Citidino, N-benzoil-5′ -O- [bis(4-metoxifenil)fenilmetil] -2′ -O- (2-metoksietil)- 5-metil-, 3′ – [2-cianoetil N,N-bis (1-metiletil) fosforamidito] (ACI)](https://cdn.globalso.com/nvchem/C50H60N5O10P-Cytidine-300x300.png)
![C41H41N5O8 Adenozino, N-benzoil-5′-O-[bis(4-metoxifenil)fenilmetil]-2′- O-(2-metoksietil)- (9CI, ACI)](https://cdn.globalso.com/nvchem/C41H41N5O8-Adenosine-300x300.jpg)
![C44H49N5O7Si Adenozino, N-benzoil-5′-O-[bis(4-metoxifenil)fenilmetil]-2′- O-[(1,1-dimetiletil)dimetilsilil]- (9CI, ACI)](https://cdn.globalso.com/nvchem/C44H49N5O7Si-Adenosine-300x300.jpg)